REST 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for REST 抗体 (N-Term) (ABIN5518090)
抗原
See all REST 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- REST Antibody - N-terminal region
-
序列
- SGSSTAEEGD FSKGPIRCDR CGYNTNRYDH YTAHLKHHTR AGDNERVYKC
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%
-
产品特性
- This is a rabbit polyclonal antibody against REST. It was validated on Western Blot.
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human REST
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32086-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- REST (RE1-Silencing Transcription Factor (REST))
-
别名
- REST
-
背景
-
Background Information: This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.
Gene Name: RE1-silencing transcription factor
Alternative Symbols: WT6, XBR, HGF5, NRSF, DFNA27, GINGF5
Protein Name: RE1-silencing transcription factor
-
分子量
- 120kDa
-
基因ID
- 5978
-
NCBI登录号
- NP_005603
-
UniProt
- Q13127
-
途径
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
-