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REST 抗体 (N-Term)

This anti-REST antibody is a 兔 多克隆 antibody detecting REST in WB. Suitable for 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼.
产品编号 ABIN5518090
发货至: 中国

Quick Overview for REST 抗体 (N-Term) (ABIN5518090)

抗原

See all REST 抗体
REST (RE1-Silencing Transcription Factor (REST))

适用

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人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 43
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克隆类型

  • 42
  • 2
多克隆

标记

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This REST antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    SGSSTAEEGD FSKGPIRCDR CGYNTNRYDH YTAHLKHHTR AGDNERVYKC

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

    产品特性

    This is a rabbit polyclonal antibody against REST. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human REST
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    REST (RE1-Silencing Transcription Factor (REST))

    别名

    REST

    背景

    This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.

    Alias Symbols: REST, NRSF, XBR,

    Protein Interaction Partner: BTRC, UBC, FBXW11, CSNK1E, NEDD8, EHMT2, EIF4A3, FBXW4, FBXW7, FBXW5, FBXW8, FBXW2, SIN3A, TERF2, GRIA2, SUB1, GTF2B, Tbp, SIN3B, HDAC1, RCOR1, SP1, SMARCE1, SMARCC2, SMARCA4, CDYL, HDAC5, HDAC4, HTT, NCOR1, KDM5C, RNF2, HDAC2, STMN2, GRM2, CTDSP1,

    Protein Size: 1097

    基因ID

    5978

    NCBI登录号

    NP_005603

    UniProt

    Q13127

    途径

    Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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