DENND3 抗体 (C-Term)
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北京 101111
Quick Overview for DENND3 抗体 (C-Term) (ABIN5518005)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- DENND3 Antibody - C-terminal region
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序列
- INCMIRVKKQ VWVGSRGLGQ GTPKGKIYVI DAERKTVEKE LVAHMDTVRT
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产品特性
- This is a rabbit polyclonal antibody against DENND3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND3
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anti-DENN/MADD Domain Containing 3 (DENND3) (pSer554) antibody
DENND3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68268-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DENND3 (DENN/MADD Domain Containing 3 (DENND3))
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别名
- DENND3
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背景
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Background Information: DENND3 is a guanine nucleotide exchange factor (GEF) activating RAB12. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, DENND3 may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
Alternative Symbols: DENND3, KIAA0870,
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分子量
- 126kDa
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基因ID
- 22898
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NCBI登录号
- NP_055772
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UniProt
- A2RUS2
抗原
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