STIL 抗体 (N-Term)
Quick Overview for STIL 抗体 (N-Term) (ABIN5517883)
抗原
See all STIL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QKLSSGKMPI HDHDSGVEDE DFSPRPIPSP HPVSQKISKI QPSVPELSLV
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产品特性
- This is a rabbit polyclonal antibody against STIL. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human STIL
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anti-SCL/TAL1 Interrupting Locus (STIL) (AA 388-637) antibody
STIL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SCL/TAL1 Interrupting Locus (STIL) antibodySTIL 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SCL/TAL1 Interrupting Locus (STIL) (AA 866-900), (C-Term) antibodySTIL 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB53223 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- STIL (SCL/TAL1 Interrupting Locus (STIL))
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别名
- STIL
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背景
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This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: SIL
Protein Size: 1287 -
基因ID
- 6491
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UniProt
- Q15468
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途径
- Tube Formation
抗原
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