SIM2 抗体 (Middle Region)
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北京 101111
Quick Overview for SIM2 抗体 (Middle Region) (ABIN5517795)
抗原
See all SIM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- SIM2 Antibody - middle region
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序列
- VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 92%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human SIM2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33297-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SIM2 (Single-Minded Homolog 2 (SIM2))
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别名
- SIM2
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背景
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Background Information: This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Gene Name: single-minded homolog 2 (Drosophila)
Alternative Symbols: SIM, bHLHe15, HMC13F06, HMC29C01
Protein Name: Single-minded homolog 2
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分子量
- 73kDa
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基因ID
- 6493
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UniProt
- Q14190
抗原
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