WDR48 抗体 (C-Term)
Quick Overview for WDR48 抗体 (C-Term) (ABIN5517644)
抗原
See all WDR48 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- YEKIINLDNE SQTTSSSNNE KPGEQEKEED IAVLAEEKIE LLCQDQVLDP
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human WDR48
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anti-WD Repeat Domain 48 (WDR48) (AA 450-677) antibody
WDR48 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) antibodyWDR48 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) (AA 603-630), (C-Term) antibodyWDR48 适用: 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28145 unconjugated
anti-WD Repeat Domain 48 (WDR48) (AA 603-630), (C-Term) antibodyWDR48 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) (AA 603-630) antibodyWDR48 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) antibodyWDR48 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat Domain 48 (WDR48) (AA 610-638), (C-Term) antibodyWDR48 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- WDR48 (WD Repeat Domain 48 (WDR48))
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别名
- WDR48
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背景
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Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46 (PubMed:18082604, PubMed:19075014, PubMed:26388029). Enhances the USP1-mediated deubiquitination of FANCD2, USP1 being almost inactive by itself (PubMed:18082604). Also activates deubiquitinating activity of complexes containing USP12 (PubMed:19075014). Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. In case of infection by Herpesvirus saimiri, may play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes. Induces lysosomal vesicle formation via interaction with Herpesvirus saimiri tyrosine kinase-interacting protein (TIP). Subsequently, TIP recruits tyrosine-protein kinase LCK, resulting in down-regulation of T-cell antigen receptor TCR. May play a role in generation of enlarged endosomal vesicles via interaction with TIP. In case of infection by papillomavirus HPV11, promotes the maintenance of the viral genome via its interaction with HPV11 helicase E1.
Alias Symbols: P80, UAF1, SPG60
Protein Size: 677 -
基因ID
- 57599
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NCBI登录号
- NM_001303402, NP_065890
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UniProt
- Q8TAF3
抗原
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