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THOC7 抗体 (C-Term)

This anti-THOC7 antibody is a 兔 多克隆 antibody detecting THOC7 in WB. Suitable for 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔 和 Pig.
产品编号 ABIN5517619
发货至: 中国

Quick Overview for THOC7 抗体 (C-Term) (ABIN5517619)

抗原

See all THOC7 抗体
THOC7 (THO Complex 7 (THOC7))

适用

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人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig

宿主

  • 22

克隆类型

  • 22
多克隆

标记

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This THOC7 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 5
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    C-Term

    序列

    SVEDKLELRR KQFHVLLSTI HELQQTLEND EKLSEVEEAQ EASMETDPKP

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against THOC7. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human THOC7
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    THOC7 (THO Complex 7 (THOC7))

    别名

    THOC7

    背景

    THOC7 is required for efficient export of polyadenylated RNA. It acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

    Alias Symbols: THOC7, NIF3L1BP1,

    Protein Interaction Partner: THOC2, RPA3, RPA2, RPA1, CKAP4, UBC, ZC3H15, TRMT112, PPIP5K2, THOC1, UBE3C, USP13, ZPR1, THOC5, VIM, S100A13, WDR36, ZCRB1, THOC3, ZNF606, THOC6, ALYREF, DDX39B, NIF3L1, CHD3, MED8, GOT2, MED18, MED22,

    Protein Size: 204

    基因ID

    80145

    NCBI登录号

    NP_079351

    UniProt

    Q6I9Y2
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