THOC7 抗体 (C-Term)
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Quick Overview for THOC7 抗体 (C-Term) (ABIN5517619)
抗原
See all THOC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SVEDKLELRR KQFHVLLSTI HELQQTLEND EKLSEVEEAQ EASMETDPKP
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against THOC7. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human THOC7
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- THOC7 (THO Complex 7 (THOC7))
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别名
- THOC7
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背景
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THOC7 is required for efficient export of polyadenylated RNA. It acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Alias Symbols: THOC7, NIF3L1BP1,
Protein Interaction Partner: THOC2, RPA3, RPA2, RPA1, CKAP4, UBC, ZC3H15, TRMT112, PPIP5K2, THOC1, UBE3C, USP13, ZPR1, THOC5, VIM, S100A13, WDR36, ZCRB1, THOC3, ZNF606, THOC6, ALYREF, DDX39B, NIF3L1, CHD3, MED8, GOT2, MED18, MED22,
Protein Size: 204 -
基因ID
- 80145
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NCBI登录号
- NP_079351
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UniProt
- Q6I9Y2
抗原
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