POLR2J3 抗体 (N-Term)

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP69943-100UG

Background Information: This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo.

Gene Name: RNA polymerase II subunit J3

Alternative Symbols: POLR2J2, RPB11b1, RPB11b2

Protein Name: DNA-directed RNA polymerase II subunit RPB11-b2