UBXN1 抗体 (N-Term)
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北京 101111
Quick Overview for UBXN1 抗体 (N-Term) (ABIN5517553)
抗原
See all UBXN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GRAEKALALT GNQGIEAAMD WLMEHEDDPD VDEPLETPLG HILGREPTSS
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产品特性
- This is a rabbit polyclonal antibody against UBXN1. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human UBXN1
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anti-UBX Domain Protein 1 (UBXN1) antibody
UBXN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UBX Domain Protein 1 (UBXN1) (AA 1-312) antibodyUBXN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-UBX Domain Protein 1 (UBXN1) (AA 215-264) antibodyUBXN1 适用: 人, 大鼠, 小鼠, Cow, 犬, 山羊, 马, 兔, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-UBX Domain Protein 1 (UBXN1) (Middle Region) antibodyUBXN1 适用: 人, 大鼠, 小鼠, Cow, 犬, 山羊, 马, 兔, Pig, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBXN1 (UBX Domain Protein 1 (UBXN1))
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别名
- UBXN1
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背景
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UBXN1 is a ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. It specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1,it leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. It is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
Alias Symbols: UBXN1, SAKS1,
Protein Interaction Partner: UBXN1, UBQLN1, FAM189A2, PLAA, TRIM39, VCP, UBE2I, UBC, PLA2G4A, MAVS, NSFL1C, STK26, TRNT1, MCTS1, TWF2, PROSC, BASP1, DENR, YWHAE, TXNRD1, TUFM, TUBB2A, PAFAH1B1, HSPA5, HMGB3, HK1, CTPS1, CAPN2, CD81, CSE1L, CLNS1A, ATP6V1A, SSSCA1, USP34, SEC22B, VPS4
Protein Size: 297 -
基因ID
- 51035
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UniProt
- Q04323
抗原
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