RASGRP1 抗体 (Middle Region)
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北京 101111
Quick Overview for RASGRP1 抗体 (Middle Region) (ABIN5517466)
抗原
See all RASGRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GLCHSSISRL KETSSHVPHE INKVLGEMTE LLSSSRNYDN YRRAYGECTD
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RASGRP1
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anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 598-797) antibody
RASGRP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 495-521) antibodyRASGRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21940 unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 594-716) antibodyRASGRP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 617-666) antibodyRASGRP1 适用: 人, 豚鼠, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) antibodyRASGRP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4630 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
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别名
- RASGRP1
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背景
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This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).
Alias Symbols: V, RASGRP, hRasGRP1, CALDAG-GEFI, CALDAG-GEFII
Protein Size: 797 -
基因ID
- 10125
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NCBI登录号
- NM_001128602, NP_001122074
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UniProt
- O95267
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
-
