PPP1R12B 抗体 (Middle Region)
Quick Overview for PPP1R12B 抗体 (Middle Region) (ABIN5517282)
抗原
See all PPP1R12B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- FNKPEEPKDE SPSSWRLGLR KTGSHNMLSE VANSREPIRD RGSSIYRSSS
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产品特性
- This is a rabbit polyclonal antibody against MYPT2. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen for Anti-PPP1R12B antibody is: synthetic peptide directed towards the Middle region of Human MYPT2
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anti-Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B) (AA 1-386) antibody
PPP1R12B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B) (AA 1-386) antibodyPPP1R12B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B) (AA 660-930) antibodyPPP1R12B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))
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别名
- PPP1R12B
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背景
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Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.
Alias Symbols: MYPT2, PP1bp55
Protein Size: 982 -
基因ID
- 4660
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UniProt
- O60237
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途径
- M Phase
抗原
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