PELI2 抗体 (N-Term)
This 兔 多克隆 anti-PELI2 antibody specifically detects PELI2 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔 和 斑马鱼 samples.
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产品编号 ABIN5517275
发货至:
中国
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Quick Overview for PELI2 抗体 (N-Term) (ABIN5517275)
抗原
See all PELI2 抗体
PELI2
(Pellino Homolog 2 (Drosophila) (PELI2))
适用
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔, 斑马鱼
宿主
兔
克隆类型
多克隆
标记
This PELI2 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- N-Term
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序列
- STISRFACRI VCDRNEPYTA RIFAAGFDSS KNIFLGEKAA KWKNPDGHMD
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against PELI2. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PELI2
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anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 1-420) antibody
PELI2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 22-51), (N-Term) antibodyPELI2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
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别名
- PELI2
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背景
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PELI2 is a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. It is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. It mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. It may be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. And it can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.
Protein Interaction Partner: SRPK1, FRYL, CREB3L3, THAP7, ERO1L, DEAF1, LAMC3, PICALM, LTBP3, IRAK1, HNRNPK, FN1, UBC, UBQLN4, IRAK4, TRAF6, NR2C2, BCL10, MYD88, IRAK2,
Protein Size: 420 -
基因ID
- 57161
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NCBI登录号
- NP_067078
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UniProt
- Q9HAT8
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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