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NSUN2 抗体 (N-Term)

This anti-NSUN2 antibody is a 兔 多克隆 antibody detecting NSUN2 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, Saccharomyces cerevisiae 和 斑马鱼.
产品编号 ABIN5517213
发货至: 中国

Quick Overview for NSUN2 抗体 (N-Term) (ABIN5517213)

抗原

See all NSUN2 抗体
NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

适用

人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, Saccharomyces cerevisiae, 斑马鱼

宿主

  • 26

克隆类型

  • 26
多克隆

标记

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
This NSUN2 antibody is un-conjugated

应用范围

  • 21
  • 17
  • 7
  • 7
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    LEKFHQFLVS ETESGNISRQ EAVSMIPPLL LNVRPHHKIL DMCAAPGSKT

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against NSUN2. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human NSUN2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

    别名

    NSUN2

    背景

    NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

    Alias Symbols: NSUN2, SAKI, TRM4,

    Protein Interaction Partner: SUMO2, SUMO3, UBC, SUMO1, NEDD8, TP53RK, PUS1, EFTUD1, XPO5, UGGT1, OSGEP, PANK4, THG1L, SH3GLB1, KIAA1279, UBXN7, TTLL12, ARPC2, ACTR2, ACTR3, FUBP1, TSN, SH3GL1, RPA1, RDX, RANGAP1, PPP2CB, PFDN5, PFDN1, NRD1, PPP1R12A, HARS, GTF2E1, CALU, CALR, UBD, VC

    Protein Size: 767

    基因ID

    54888

    NCBI登录号

    NP_060225

    UniProt

    Q08J23
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