MATK 抗体 (C-Term)
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Quick Overview for MATK 抗体 (C-Term) (ABIN5517155)
抗原
See all MATK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SSCWEAEPAR RPPFRKLAEK LARELRSAGA PASVSGQDAD GSTSPRSQEP
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产品特性
- This is a rabbit polyclonal antibody against MATK. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MATK
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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别名
- MATK
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背景
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The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Alias Symbols: MATK, CTK, HYL,
Protein Interaction Partner: BRCA1, UBC, HSP90AA1, ERBB2, MYC, CACNA1A, PXN, PTK2B, NTRK1, SRC, CD36, LYN, KIT, EWSR1,
Protein Size: 507 -
基因ID
- 4145
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NCBI登录号
- NP_647612
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UniProt
- P42679
抗原
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