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COQ6 抗体 (N-Term)

This anti-COQ6 antibody is a 兔 多克隆 antibody detecting COQ6 in WB. Suitable for 人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马 和 Saccharomyces cerevisiae.
产品编号 ABIN5517062
发货至: 中国

Quick Overview for COQ6 抗体 (N-Term) (ABIN5517062)

抗原

See all COQ6 抗体
COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

适用

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人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马, Saccharomyces cerevisiae

宿主

  • 28

克隆类型

  • 28
多克隆

标记

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  • 3
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This COQ6 antibody is un-conjugated

应用范围

  • 24
  • 15
  • 10
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Western Blotting (WB)
  • 抗原表位

    • 8
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    • 1
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    N-Term

    序列

    ILLLEAGPKK VLEKLSETYS NRVSSISPGS ATLLSSFGAW DHICNMRYRA

    预测反应

    Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 80%

    产品特性

    This is a rabbit polyclonal antibody against COQ6. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human COQ6
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    COQ6 (Coenzyme Q6, Monooxygenase (COQ6))

    别名

    COQ6

    背景

    The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Alias Symbols: CGI10, COQ10D6

    Protein Interaction Partner: SUMO1, UBC, NEDD8, APP, CDK2, ZBTB16, ARSE,

    Protein Size: 443

    基因ID

    51004

    NCBI登录号

    NM_182480, NP_872286
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