FBXL15 抗体 (N-Term)
This anti-FBXL15 antibody is a 兔 多克隆 antibody detecting FBXL15 in WB. Suitable for 人, Cow, 犬, 山羊, 马, 小鼠, 兔 和 大鼠.
Quick Overview for FBXL15 抗体 (N-Term) (ABIN5517039)
抗原
See all FBXL15 抗体
FBXL15
(F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
适用
人, Cow, 犬, 山羊, 马, 小鼠, 兔, 大鼠
宿主
兔
克隆类型
多克隆
标记
This FBXL15 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- N-Term
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序列
- PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR
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预测反应
- Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
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anti-F-Box and Leucine-Rich Repeat Protein 15 (FBXL15) (AA 252-280), (C-Term) antibody
FBXL15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB26324 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
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别名
- FBXL15
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背景
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FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.
Alias Symbols: FBXO37, Fbl15, JET, PSD
Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,
Protein Size: 300 -
基因ID
- 79176
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NCBI登录号
- NM_024326, NP_077302
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UniProt
- Q9H469
抗原
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