Leupaxin 抗体 (C-Term)
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Quick Overview for Leupaxin 抗体 (C-Term) (ABIN5516889)
抗原
See all Leupaxin (LPXN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- HGCGQPITGR CISAMGYKFH PEHFVCAFCL TQLSKGIFRE QNDKTYCQPC
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产品特性
- This is a rabbit polyclonal antibody against LPXN. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human LPXN
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Leupaxin (LPXN)
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别名
- LPXN
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背景
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The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: LPXN, LDLP,
Protein Interaction Partner: LMO1, HOXC9, RUNX1T1, TXLNB, PLEKHH2, PLEKHN1, SFI1, NDN, SUMO1, UBC, NEDD8, HOXA1, ZNF175, MAP2K7, HDAC6, PTK2, MAPK6, IKBKG, ZNF426, IMP3, POM121, PHF21A, LIMS1, PTK2B, PTPN12, ITGA4,
Protein Size: 386 -
基因ID
- 9404
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NCBI登录号
- NP_004802
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UniProt
- O60711
抗原
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