RASA1 抗体 (N-Term)
Quick Overview for RASA1 抗体 (N-Term) (ABIN5516840)
抗原
See all RASA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GTVDEGDSLD GPEYEEEEVA IPLTAPPTNQ WYHGKLDRTI AEERLRQAGK
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产品特性
- This is a rabbit polyclonal antibody against RASA1. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human RASA1
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anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) antibody
RASA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) antibodyRASA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 403-596) antibodyRASA1 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 201-500) antibodyRASA1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) antibodyRASA1 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) antibodyRASA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (C-Term) antibodyRASA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 140-220) antibodyRASA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 953-1002) antibodyRASA1 适用: 人, 大鼠, 小鼠, 犬, 小鸡, 豚鼠, 马, 兔, 斑马鱼, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) antibodyRASA1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
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别名
- RASA1
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背景
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The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
Alias Symbols: RASA1, GAP, RASA,
Protein Interaction Partner: ARHGAP35, DOK1, KHDRBS1, DOK2, PLCG1, EGFR, ABL1, Mbp, ERBB4, ERBB3, ERBB2, APP, SOCS1, UBC, SPSB1, ZNF579, BBS10, TRMT2A, EIF1, SERPINA4, XRCC6, EZH2, NCK1, BTRC, NFKBIA, DOK4, AFAP1L2, DNAJA3, G3BP1, PAG1, AURKB, MAP4K4, SOCS3, BIRC5, ARHGAP1, ARHGAP5,
Protein Size: 1047 -
基因ID
- 5921
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UniProt
- P20936
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途径
- Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
抗原
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