GZMH 抗体 (C-Term)
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Quick Overview for GZMH 抗体 (C-Term) (ABIN5516766)
抗原
See all GZMH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- EVLLTVQKDC QCERLFHGNY SRATEICVGD PKKTQTGFKG DSGGPLVCKD
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产品特性
- This is a rabbit polyclonal antibody against GZMH. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human GZMH
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
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别名
- GZMH
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背景
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The protein encoded by this gene is a member of the granzyme family. Members of this family are highly conserved serine proteases that eliminate transformed cells and virus-infected cells. This protein, which has chymotrypsin-like activity, has a preference for bulky aromatic amino acids at the P1 position and for acidic residues at the P3' and P4' positions. This protein is reported to be constitutively expressed in NK cells and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Alias Symbols: GZMH, CGL2, CTSGL2,
Protein Interaction Partner: SSB,
Protein Size: 246 -
基因ID
- 2999
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NCBI登录号
- NP_219491
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UniProt
- P20718
抗原
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