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KRIT1 抗体 (C-Term)

KRIT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5516696
发货至: 中国
  • 抗原 See all KRIT1 抗体
    KRIT1 (KRIT1, Ankyrin Repeat Containing (KRIT1))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 28
    • 21
    • 6
    宿主
    • 39
    • 4
    克隆类型
    • 40
    • 3
    多克隆
    标记
    • 15
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KRIT1 antibody is un-conjugated
    应用范围
    • 36
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    LLQIVYGNYE SKKHKQGFLN EENLKSIVPV TKLKSKAPHW TNRILHEYKN
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human KRIT1
    Top Product
    Discover our top product KRIT1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    KRIT1 (KRIT1, Ankyrin Repeat Containing (KRIT1))
    别名
    KRIT1 (KRIT1 产品)
    别名
    CAM antibody, CCM1 antibody, 2010007K12Rik antibody, A630036P20Rik antibody, AA432855 antibody, AI450393 antibody, AI643869 antibody, BB155247 antibody, BB235701 antibody, Ccm1 antibody, RGD1305929 antibody, krit1 antibody, fb36f07 antibody, san antibody, santa antibody, wu:fb36f07 antibody, zgc:63585 antibody, KRIT1, ankyrin repeat containing antibody, KRIT1 antibody, Krit1 antibody, krit1 antibody
    背景
    This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene.

    Alias Symbols: CAM, CCM1

    Protein Size: 529
    基因ID
    889
    NCBI登录号
    NM_001013406
    途径
    Cell RedoxHomeostasis
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