SLC16A2/MCT8 抗体 (N-Term)
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Quick Overview for SLC16A2/MCT8 抗体 (N-Term) (ABIN5516550)
抗原
See all SLC16A2/MCT8 (SLC16A2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- EPEPVPVPPP EPQPEPQPLP DPAPLPELEF ESERVHEPEP TPTVETRGTA
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SLC16A2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))
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别名
- SLC16A2
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背景
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This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome.
Alias Symbols: AHDS, MCT7, MCT8, XPCT, MCT 7, MCT 8, MRX22, DXS128, DXS128E
Protein Size: 539 -
基因ID
- 6567
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NCBI登录号
- NM_006517, NP_006508
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UniProt
- P36021
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途径
- Hormone Transport
抗原
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