MAPK8IP1 抗体 (N-Term)
Quick Overview for MAPK8IP1 抗体 (N-Term) (ABIN5516519)
抗原
See all MAPK8IP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GSGDTYRPKR PTTLNLFPQV PRSQDTLNNN SLGKKHSWQD RVSRSSSPLK
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAPK8IP1
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anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) antibody
MAPK8IP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498), (C-Term) antibodyMAPK8IP1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB23000 unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (Tyr466) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 69-118) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) antibodyMAPK8IP1 适用: 人 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 425-524) antibodyMAPK8IP1 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (pThr103) antibodyMAPK8IP1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 265-279) antibodyVerified MAPK8IP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (pThr103) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498) antibodyMAPK8IP1 适用: 人 WB, IF, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
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别名
- MAPK8IP1
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背景
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This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.
Alias Symbols: IB1, JIP1, JIP-1, PRKM8IP
Protein Size: 711 -
基因ID
- 9479
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NCBI登录号
- NM_005456, NP_005447
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UniProt
- Q9UQF2
抗原
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