ARVCF 抗体 (C-Term)
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Quick Overview for ARVCF 抗体 (C-Term) (ABIN5516447)
抗原
See all ARVCF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GPDGYSTVDR RERRPRGASS AGEASEKEPL KLDPSRKAPP PGPSRPAVRL
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产品特性
- This is a rabbit polyclonal antibody against ARVCF. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ARVCF
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))
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别名
- ARVCF
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背景
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Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein.
Alias Symbols: Name=ARVCF,
Protein Interaction Partner: ERBB2IP, UBC, LNX1, TJP1, CDH1, CDH2, CDH15,
Protein Size: 962 -
基因ID
- 421
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NCBI登录号
- NP_001661
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UniProt
- O00192
抗原
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