Chitotriosidase 1 抗体 (C-Term)
Quick Overview for Chitotriosidase 1 抗体 (C-Term) (ABIN5516322)
抗原
See all Chitotriosidase 1 (CHIT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GTPELEVPKP GQPSEPEHGP SPGQDTFCQG KADGLYPNPR ERSSFYSCAA
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CHIT1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
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别名
- CHIT1
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背景
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Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Alias Symbols: CHI3, CHIT, CHITD
Protein Size: 466 -
基因ID
- 1118
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NCBI登录号
- NM_001256125, NP_001243054
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UniProt
- Q13231
抗原
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