PAK6 抗体 (N-Term)
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Quick Overview for PAK6 抗体 (N-Term) (ABIN5516056)
抗原
See all PAK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RVQLQPMKTV VRGSAMPVDG YISGLLNDIQ KLSVISSNTL RGRSPTSRRR
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产品特性
- This is a rabbit polyclonal antibody against PAK6. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PAK6
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAK6 (P21-Activated Kinase 6 (PAK6))
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别名
- PAK6
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背景
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This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
Alias Symbols: PAK6, PAK5,
Protein Interaction Partner: RHOJ, RAC1, NEK6, SEMA3B, TPD52L1, SNX2, HSP90AA1, CDK1, MDM2, AR, APP, LNX1, MYC, MAPK14, CDC42, ESR1, AKT1, YWHAQ,
Protein Size: 681 -
基因ID
- 56924
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NCBI登录号
- NP_064553
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UniProt
- Q9NQU5
抗原
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