GNRHR 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for GNRHR 抗体 (C-Term) (ABIN5516035)
抗原
See all GNRHR 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- ICNAKIIFTL TRVLHQDPHE LQLNQSKNNI PRARLKTLKM TVAFATSFTV
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human GNRHR
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
-
别名
- GNRHR
-
背景
-
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.
Alias Symbols: HH7, GRHR, LRHR, LHRHR, GNRHR1
Protein Size: 328 -
基因ID
- 2798
-
NCBI登录号
- NM_000406, NP_000397
-
UniProt
- P30968
抗原
-