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PDGFRA 抗体 (C-Term)

This anti-PDGFRA antibody is a 兔 多克隆 antibody detecting PDGFRA in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠 和 斑马鱼.
产品编号 ABIN5515866
发货至: 中国
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Quick Overview for PDGFRA 抗体 (C-Term) (ABIN5515866)

抗原

See all PDGFRA 抗体
PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

适用

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人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This PDGFRA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    SGYIIPLPDI DPVPEEEDLG KRNRHSSQTS EESAIETGSS SSTFIKREDE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against PGFRA. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen for Anti-PDGFRA antibody is: synthetic peptide directed towards the C-terminal region of Human PGFRA
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

    别名

    PDGFRA

    背景

    This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

    Alias Symbols: CD140A, PDGFR2, PDGFR-2, RHEPDGFRA

    Protein Interaction Partner: CCDC155, SRPK1, FBXO25, ULBP2, UBC, TGFBR2, PIK3R1, KIT, Nedd4, GRB2, PTEN, SHF, SNX6, PDGFC, SNX4, SNX2, SLC9A3R1, STAT5B, CRKL, GRB14, STAT5A, CAV1, STAT1, SHB, ITGAV, PDGFB, PTPN11, PDGFRA, ITGB3, PDGFA, PDGFRB, PLCG1, CBL, CRK, JAK1, STAT3, CAV3,

    Protein Size: 1089

    基因ID

    5156

    UniProt

    P16234

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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