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ADD2 抗体 (C-Term)

ADD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515464
发货至: 中国
  • 抗原 See all ADD2 抗体
    ADD2 (Adducin 2 (Beta) (ADD2))
    抗原表位
    • 15
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 28
    • 24
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 41
    • 2
    克隆类型
    • 43
    多克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADD2 antibody is un-conjugated
    应用范围
    • 35
    • 13
    • 13
    • 11
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    SAGPQSQLLA SVIAEKSRSP STESQLMSKG DEDTKDDSEE TVPNPFSQLT
    产品特性
    This is a rabbit polyclonal antibody against ADDB. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen for Anti-ADD2 antibody is: synthetic peptide directed towards the C-terminal region of Human ADDB
    Top Product
    Discover our top product ADD2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ADD2 (Adducin 2 (Beta) (ADD2))
    别名
    ADD2 (ADD2 产品)
    别名
    si:dkey-202n14.5 antibody, ADDB antibody, 2900072M03Rik antibody, add97 antibody, beta-ADD antibody, adducin 2 antibody, adducin 2 (beta) antibody, ADD2 antibody, add2 antibody, Add2 antibody
    背景
    Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described.

    Alias Symbols: ADDB,

    Protein Size: 726
    基因ID
    119
    UniProt
    P35612
    途径
    Regulation of Actin Filament Polymerization
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