ADD2 抗体 (C-Term)
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北京 101111
Quick Overview for ADD2 抗体 (C-Term) (ABIN5515464)
抗原
See all ADD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SAGPQSQLLA SVIAEKSRSP STESQLMSKG DEDTKDDSEE TVPNPFSQLT
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产品特性
- This is a rabbit polyclonal antibody against ADDB. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen for Anti-ADD2 antibody is: synthetic peptide directed towards the C-terminal region of Human ADDB
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anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibody
ADD2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 1-726) antibodyADD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 401-500) antibodyADD2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) antibodyADD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 1-726) antibodyADD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 648-697) antibodyADD2 适用: 人, Cow, 马, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Middle Region) antibodyADD2 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 豚鼠, 兔 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ADD2 (Adducin 2 (Beta) (ADD2))
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别名
- ADD2
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背景
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Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described.
Alias Symbols: ADDB,
Protein Size: 726 -
基因ID
- 119
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UniProt
- P35612
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途径
- Regulation of Actin Filament Polymerization
抗原
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