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CCAR1 抗体 (C-Term)

This anti-CCAR1 antibody is a 兔 多克隆 antibody detecting CCAR1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, Pig 和 豚鼠.
产品编号 ABIN5515401
发货至: 中国

Quick Overview for CCAR1 抗体 (C-Term) (ABIN5515401)

抗原

See all CCAR1 抗体
CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

适用

人, 小鼠, 大鼠, 犬, 兔, 马, Cow, Pig, 豚鼠

宿主

  • 37
  • 1

克隆类型

  • 38
多克隆

标记

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This CCAR1 antibody is un-conjugated

应用范围

  • 15
  • 13
  • 13
  • 10
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  • 8
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  • 1
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    YDPMEAEEAE DEEDDRDEEE MTKRDDKRDI NRYCKERPSK DKEKEKTQMI

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against CCAR1. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCAR1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

    别名

    CCAR1

    背景

    CCAR1 associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. It is recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. It also functions as a p53 coactivator. It may thus play an important role in transcriptional regulation (By similarity). It may be involved in apoptosis signaling in the presence of the reinoid CD437. It apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. And it plays a role in cell cycle progression and/or cell proliferation.

    Alias Symbols: CARP1, DIS

    Protein Interaction Partner: PIH1D3, GOLGA2, SUMO2, SUMO3, UBC, TP53, MDM2, U2AF2, CHERP, UBL4A, RBM10, RNF113A, HNRNPK, SMURF1, BARD1, SIRT7, SF3A2, Kif23, FYCO1, CASP10, SFN, YWHAQ,

    Protein Size: 1150

    基因ID

    55749

    NCBI登录号

    NP_060707

    UniProt

    Q8IX12
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