CCAR1 抗体 (C-Term)
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Quick Overview for CCAR1 抗体 (C-Term) (ABIN5515401)
抗原
See all CCAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- YDPMEAEEAE DEEDDRDEEE MTKRDDKRDI NRYCKERPSK DKEKEKTQMI
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against CCAR1. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCAR1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
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别名
- CCAR1
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背景
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CCAR1 associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. It is recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. It also functions as a p53 coactivator. It may thus play an important role in transcriptional regulation (By similarity). It may be involved in apoptosis signaling in the presence of the reinoid CD437. It apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. And it plays a role in cell cycle progression and/or cell proliferation.
Alias Symbols: CARP1, DIS
Protein Interaction Partner: PIH1D3, GOLGA2, SUMO2, SUMO3, UBC, TP53, MDM2, U2AF2, CHERP, UBL4A, RBM10, RNF113A, HNRNPK, SMURF1, BARD1, SIRT7, SF3A2, Kif23, FYCO1, CASP10, SFN, YWHAQ,
Protein Size: 1150 -
基因ID
- 55749
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NCBI登录号
- NP_060707
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UniProt
- Q8IX12
抗原
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