Stanniocalcin 2 抗体 (N-Term)
Quick Overview for Stanniocalcin 2 抗体 (N-Term) (ABIN5515182)
抗原
See all Stanniocalcin 2 (STC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ATFDPARGTD ATNPPEGPQD RSSQQKGRLS LQNTAEIQHC LVNAGDVGCG
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human STC2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Stanniocalcin 2 (STC2)
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别名
- STC2
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背景
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This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Alias Symbols: STC-2, STCRP
Protein Size: 302 -
基因ID
- 8614
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NCBI登录号
- NM_003714, NP_003705
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UniProt
- O76061
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途径
- Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
抗原
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