RASA3 抗体 (N-Term)
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Quick Overview for RASA3 抗体 (N-Term) (ABIN5515101)
抗原
See all RASA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- YEAWYFLQPR DNGSKSLKPD DLGSLRLNVV YTEDHVFSSD YYSPLRDLLL
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产品特性
- This is a rabbit polyclonal antibody against RASA3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human RASA3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RASA3 (RAS P21 Protein Activator 3 (RASA3))
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别名
- RASA3
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背景
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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
Alias Symbols: RASA3,
Protein Interaction Partner: UBC, ARHGAP19, SPTB, APP, FES, RAP1A, GNB2L1, HCK,
Protein Size: 834 -
基因ID
- 22821
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NCBI登录号
- NP_031394
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UniProt
- Q14644
抗原
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