RAB43 抗体 (C-Term)
Quick Overview for RAB43 抗体 (C-Term) (ABIN5515092)
抗原
See all RAB43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ETSAKDSSNV EEAFLRVATE LIMRHGGPLF SEKSPDHIQL NSKDIGEGWG
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产品特性
- This is a rabbit polyclonal antibody against RAB43. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human RAB43
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anti-RAB43, Member RAS Oncogene Family (RAB43) (AA 113-210) antibody
RAB43 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5G4 unconjugated
anti-RAB43, Member RAS Oncogene Family (RAB43) (Internal Region) antibodyRAB43 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB43, Member RAS Oncogene Family (RAB43) (AA 1-212) antibodyRAB43 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB43, Member RAS Oncogene Family (RAB43) (AA 1-212) antibodyRAB43 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAB43 (RAB43, Member RAS Oncogene Family (RAB43))
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别名
- RAB43
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背景
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The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. RAB43 is involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. It plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
Alias Symbols: RAB41
Protein Size: 212 -
基因ID
- 339122
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NCBI登录号
- NP_940892
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UniProt
- Q86YS6
抗原
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