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PTPMT1 抗体 (N-Term)

The 兔 多克隆 anti-PTPMT1 antibody is suitable to detect PTPMT1 in samples from 人. It has been validated for WB.
产品编号 ABIN5515057
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PTPMT1 抗体 (N-Term) (ABIN5515057)

抗原

See all PTPMT1 抗体
PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This PTPMT1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    原理

    PTPMT1 Antibody - N-terminal region

    序列

    LFYPTLLYTL FRGKVPGRAH RDWYHRIDPT VLLGALPLRS LTRQLVQDEN

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PTPMT1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP79956-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

    别名

    PTPMT1

    背景

    Background Information: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity).

    Gene Name: protein tyrosine phosphatase, mitochondrial 1

    Alternative Symbols: MOSP, PLIP, DUSP23, PNAS-129

    Protein Name: phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

    分子量

    23 kDa

    基因ID

    114971

    NCBI登录号

    NP_001137456

    UniProt

    Q8WUK0

    途径

    Inositol Metabolic Process
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