PTPMT1 抗体 (N-Term)
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北京 101111
Quick Overview for PTPMT1 抗体 (N-Term) (ABIN5515057)
抗原
See all PTPMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PTPMT1 Antibody - N-terminal region
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序列
- LFYPTLLYTL FRGKVPGRAH RDWYHRIDPT VLLGALPLRS LTRQLVQDEN
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PTPMT1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP79956-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))
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别名
- PTPMT1
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背景
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Background Information: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity).
Gene Name: protein tyrosine phosphatase, mitochondrial 1
Alternative Symbols: MOSP, PLIP, DUSP23, PNAS-129
Protein Name: phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
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分子量
- 23 kDa
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基因ID
- 114971
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NCBI登录号
- NP_001137456
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UniProt
- Q8WUK0
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途径
- Inositol Metabolic Process
抗原
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