UBTF 抗体 (C-Term)
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Quick Overview for UBTF 抗体 (C-Term) (ABIN5515000)
抗原
See all UBTF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SEDGGDSSES SSEDESEDGD ENEEDDEDED DDEDDDEDED NESEGSSSSS
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 93%, Yeast: 86%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against UBF1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBF1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))
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别名
- UBF1
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背景
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This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.
Alias Symbols: UBTF, UBF, UBF1,
Protein Interaction Partner: UBC, MDM2, RNF2, Dlg4, ESR1, CDK4, CDK2, CCNE1, CCND1, WDR70, YEATS4, RB1, GRK5, KAT5, SIRT7, POLR1A, MYBBP1A, HDAC1, RUNX2, SUMO2, SMARCA5, MAPK3, MAPK1, SUMO1, PIK3CA, IRS1, TAF1D, tat, MCRS1, TLE1, ACTN4, POLR1E, CHGB, SMURF1, TCOF1, MAD1L1, ZMYM2, SER
Protein Size: 764 -
基因ID
- 7343
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NCBI登录号
- XP_006722124
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UniProt
- P17480
抗原
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