MNDA 抗体 (Middle Region)
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Quick Overview for MNDA 抗体 (Middle Region) (ABIN5514973)
抗原
See all MNDA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KRKTPNKEKT EAKRNKVSQE QSKPPGPSGA STSAAVDHPP LPQTSSSTPS
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MNDA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
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别名
- MNDA
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背景
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The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.
Alias Symbols: PYHIN3
Protein Size: 407 -
基因ID
- 4332
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NCBI登录号
- NM_002432, NP_002423
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UniProt
- P41218
抗原
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