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MNDA 抗体 (Middle Region)

This anti-MNDA antibody is a 兔 多克隆 antibody detecting MNDA in WB. Suitable for 人.
产品编号 ABIN5514973
发货至: 中国

Quick Overview for MNDA 抗体 (Middle Region) (ABIN5514973)

抗原

See all MNDA 抗体
MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

适用

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宿主

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克隆类型

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多克隆

标记

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This MNDA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    KRKTPNKEKT EAKRNKVSQE QSKPPGPSGA STSAAVDHPP LPQTSSSTPS

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MNDA
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

    别名

    MNDA

    背景

    The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.

    Alias Symbols: PYHIN3

    Protein Size: 407

    基因ID

    4332

    NCBI登录号

    NM_002432, NP_002423

    UniProt

    P41218
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