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KLC1 抗体 (C-Term)

This anti-KLC1 antibody is a 兔 多克隆 antibody detecting KLC1 in WB. Suitable for 人.
产品编号 ABIN5514913
发货至: 中国

Quick Overview for KLC1 抗体 (C-Term) (ABIN5514913)

抗原

See all KLC1 抗体
KLC1 (Kinesin Light Chain 1 (KLC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This KLC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    ETLYKEILTR AHEREFGSVD DENKPIWMHA EEREECKGKQ KDGTSFGEYG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human KLC1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    KLC1 (Kinesin Light Chain 1 (KLC1))

    别名

    KLC1

    背景

    Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.

    Alias Symbols: KLC, KNS2, KNS2A,

    Protein Interaction Partner: CCDC114, KRT31, BNIP2, UBC, EZH2, TLE3, KIF5B, DIAPH1, COPB1, ARCN1, KLC4, KLC2, SMEK2, PTPN23, COPZ1, APP, RIC3, BSDC1, FAM63B, PRKAG3, LDLRAP1, RASSF8, YWHAE, SKP1, SNCA, KIF5A, MAPK6, YWHAB, LRSAM1, MAPK8IP3, PLEKHM2, CLSTN1, SPAG9, MAPK8IP2, MAPK8IP1,

    Protein Size: 551

    基因ID

    3831

    NCBI登录号

    NM_001130107, NP_005543

    途径

    Ribonucleoprotein Complex Subunit Organization
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