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GRM2 抗体 (C-Term)

GRM2 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514828
发货至: 中国
  • 抗原 See all GRM2 抗体
    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
    抗原表位
    • 15
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 54
    • 48
    • 31
    • 16
    • 16
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马
    宿主
    • 62
    • 6
    • 1
    克隆类型
    • 58
    • 11
    多克隆
    标记
    • 29
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRM2 antibody is un-conjugated
    应用范围
    • 32
    • 24
    • 21
    • 13
    • 13
    • 9
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    AWLVVEAPGT GKETAPERRE VVTLRCNHRD ASMLGSLAYN VLLIALCTLY
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against GRM2. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human GRM2
    Top Product
    Discover our top product GRM2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
    别名
    GRM2 (GRM2 产品)
    背景
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: GPRC1B, MGLUR2

    Protein Interaction Partner: NAALADL2, UBQLN1, GRASP, RGS12, GNAQ, GNA15, SMARCC2, SMARCA4, REST,

    Protein Size: 872
    基因ID
    2912
    NCBI登录号
    XP_006713184
    UniProt
    Q14416
    途径
    cAMP Metabolic Process, Dicarboxylic Acid Transport
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