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GRM2 抗体 (C-Term)

This anti-GRM2 antibody is a 兔 多克隆 antibody detecting GRM2 in WB. Suitable for 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠 和 马.
产品编号 ABIN5514828
发货至: 中国

Quick Overview for GRM2 抗体 (C-Term) (ABIN5514828)

抗原

See all GRM2 抗体
GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

适用

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人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This GRM2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    AWLVVEAPGT GKETAPERRE VVTLRCNHRD ASMLGSLAYN VLLIALCTLY

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GRM2. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human GRM2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

    别名

    GRM2

    背景

    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: GPRC1B, MGLUR2

    Protein Interaction Partner: NAALADL2, UBQLN1, GRASP, RGS12, GNAQ, GNA15, SMARCC2, SMARCA4, REST,

    Protein Size: 872

    基因ID

    2912

    NCBI登录号

    XP_006713184

    UniProt

    Q14416

    途径

    cAMP Metabolic Process, Dicarboxylic Acid Transport
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