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PKM 抗体 (C-Term)

The 兔 多克隆 anti-PKM antibody (ABIN5514803) specifically detects PKM in WB. The antibody is reactive with 人 samples.
产品编号 ABIN5514803
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PKM 抗体 (C-Term) (ABIN5514803)

抗原

See all PKM 抗体
PKM (Pyruvate Kinase M1/2 (PKM))

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This PKM antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    PKM Antibody - C-terminal region

    序列

    VICATQMLES MIKKPRPTRA EGSDVANAVL DGADCIMLSG ETAKGDYPLE

    产品特性

    This is a rabbit polyclonal antibody against KPYM. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human KPYM
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75032-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PKM (Pyruvate Kinase M1/2 (PKM))

    别名

    PKM

    背景

    Background Information: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

    Gene Name: pyruvate kinase M1/2

    Alternative Symbols: PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30

    Protein Name: pyruvate kinase PKM

    分子量

    58kDa

    基因ID

    5315

    NCBI登录号

    XP_005254502

    UniProt

    P14618

    途径

    Warburg Effect
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