PKM 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for PKM 抗体 (C-Term) (ABIN5514803)
抗原
See all PKM 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- VICATQMLES MIKKPRPTRA EGSDVANAVL DGADCIMLSG ETAKGDYPLE
-
产品特性
- This is a rabbit polyclonal antibody against KPYM. It was validated on Western Blot.
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human KPYM
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- PKM (Pyruvate Kinase M1/2 (PKM))
-
别名
- KPYM
-
背景
-
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Alias Symbols: PKM, OIP3, PK2, PK3, PKM2,
Protein Interaction Partner: LNX1, NXT2, HUWE1, ISG15, UBC, POLE2, FUS, SUMO2, SUMO3, STAU1, MDM2, SUZ12, EZH2, IPO11, TWF2, PDLIM5, NPLOC4, PLIN3, UBA2, EIF4A3, ANP32A, SRP14, RAD23B, PPP1CA, PIN1, CTPS1, CBS, CAPZA2, ACAT2, NLK, FBXO6, YWHAQ, RAF1, IGSF8, HDAC6, MAPK7, NPM1, CDK2,
Protein Size: 531 -
基因ID
- 5315
-
NCBI登录号
- XP_005254502
-
UniProt
- P14618
-
途径
- Warburg Effect
抗原
-