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PNP 抗体 (Middle Region)

The 兔 多克隆 anti-PNP antibody (ABIN5514791) specifically detects PNP in WB. The antibody is reactive with 人 samples.
产品编号 ABIN5514791
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PNP 抗体 (Middle Region) (ABIN5514791)

抗原

See all PNP 抗体
PNP (Purine Nucleoside Phosphorylase (PNP))

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This PNP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    原理

    PNP Antibody - middle region

    序列

    IMLIRDHINL PGFSGQNPLR GPNDERFGDR FPAMSDAYDR TMRQRALSTW

    产品特性

    This is a rabbit polyclonal antibody against PNPH. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of Human PNPH
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75005-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PNP (Purine Nucleoside Phosphorylase (PNP))

    别名

    PNP

    背景

    Background Information: This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

    Gene Name: purine nucleoside phosphorylase

    Alternative Symbols: NP, PUNP, PRO1837

    Protein Name: purine nucleoside phosphorylase

    分子量

    31kDa

    基因ID

    4860

    NCBI登录号

    NP_000261

    UniProt

    P00491

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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