GPS2 抗体 (C-Term)
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北京 101111
Quick Overview for GPS2 抗体 (C-Term) (ABIN5514785)
抗原
See all GPS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- GPS2 Antibody - C-terminal region
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序列
- TAQPPPHYGP TQPAYSPSQQ LRAPSAFPAV QYLSQPQPQP YAVHGHFQPT
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产品特性
- This is a rabbit polyclonal antibody against GPS2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPS2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72703-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GPS2 (G Protein Pathway Suppressor 2 (GPS2))
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别名
- GPS2
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背景
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Background Information: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Alternative Symbols: AMF-1
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分子量
- 35kDa
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基因ID
- 2874
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NCBI登录号
- XP_005256674
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UniProt
- Q13227
抗原
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