LZTS1 抗体 (N-Term)
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北京 101111
Quick Overview for LZTS1 抗体 (N-Term) (ABIN5514757)
抗原
See all LZTS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LKKLNRYSDG LLRFGFSQDS GHGKSSSKMG KSEDFFYIKV SQKARGSHHP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 79%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against LZTS1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human LZTS1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
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别名
- LZTS1
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背景
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This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Alias Symbols: LZTS1, FEZ1,
Protein Interaction Partner: EEF1G, CDC25C, CDK1,
Protein Size: 596 -
基因ID
- 11178
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NCBI登录号
- XP_005273451
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UniProt
- Q9Y250
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途径
- Synaptic Membrane
抗原
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