DUOX1 抗体 (N-Term)
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Quick Overview for DUOX1 抗体 (N-Term) (ABIN5514730)
抗原
See all DUOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LLVGAWTPLG AQNPISWEVQ RFDGWYNNLM EHRWGSKGSR LQRLVPASYA
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DUOX1
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anti-Dual Oxidase 1 (DUOX1) (AA 1312-1551) antibody
DUOX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Oxidase 1 (DUOX1) (AA 972-985) antibodyVerified DUOX1 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Dual Oxidase 1 (DUOX1) (Internal Region) antibodyVerified DUOX1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Dual Oxidase 1 (DUOX1) (AA 941-1028) antibodyDUOX1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DUOX1 (Dual Oxidase 1 (DUOX1))
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别名
- DUOX1
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背景
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The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Alias Symbols: LNOX1, THOX1, NOXEF1
Protein Size: 1551 -
基因ID
- 53905
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NCBI登录号
- NM_017434, NP_059130
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UniProt
- Q9NRD9
抗原
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