DRD3 抗体 (N-Term)
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Quick Overview for DRD3 抗体 (N-Term) (ABIN5514728)
抗原
See all DRD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ASLSQLSSHL NYTCGAENST GASQARPHAY YALSYCALIL AIVFGNGLVC
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DRD3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DRD3 (Dopamine Receptor D3 (DRD3))
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别名
- DRD3
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背景
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This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Alias Symbols: D3DR, ETM1, FET1
Protein Size: 400 -
基因ID
- 1814
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NCBI登录号
- NM_000796, NP_000787
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UniProt
- P35462
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity
抗原
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