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CKMT1A 抗体 (C-Term)

CKMT1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514690
发货至: 中国
  • 抗原 See all CKMT1A 抗体
    CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
    抗原表位
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 20
    • 8
    • 1
    宿主
    • 17
    • 3
    克隆类型
    • 17
    • 3
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    This CKMT1A antibody is un-conjugated
    应用范围
    • 15
    • 15
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    QKRGTGGVDT AATGGVFDIS NLDRLGKSEV ELVQLVIDGV NYLIDCERRL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CKMT1A
    Top Product
    Discover our top product CKMT1A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
    别名
    CKMT1A (CKMT1A 产品)
    别名
    CKMT1 antibody, Mt-CK antibody, ScCKmit antibody, UbCKmit antibody, mi-CK antibody, Ckmt1 antibody, CKMT1B antibody, Mia-CK antibody, U-MtCK antibody, creatine kinase, mitochondrial 1A antibody, creatine kinase U-type, mitochondrial-like antibody, creatine kinase, mitochondrial 1, ubiquitous antibody, creatine kinase U-type, mitochondrial antibody, CKMT1A antibody, LOC100228000 antibody, Ckmt1 antibody, LOC100725326 antibody
    背景
    Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

    Alias Symbols: CKMT1, U-MtCK, mia-CK

    Protein Interaction Partner: UBC, MDM2, SUZ12, gag-pol, CUL3, ASB9, VDAC1, SLC25A5, CKMT1A,

    Protein Size: 417
    基因ID
    548596
    NCBI登录号
    NM_001015001, NP_001015001
    UniProt
    P12532
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