CKMT1A 抗体 (C-Term)
Quick Overview for CKMT1A 抗体 (C-Term) (ABIN5514690)
抗原
See all CKMT1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QKRGTGGVDT AATGGVFDIS NLDRLGKSEV ELVQLVIDGV NYLIDCERRL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CKMT1A
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anti-Creatine Kinase, Mitochondrial 1A (CKMT1A) (AA 41-250) antibody
CKMT1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1A (CKMT1A) (AA 40-417) antibodyCKMT1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1A (CKMT1A) (AA 258-417) antibodyCKMT1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Creatine Kinase, Mitochondrial 1A (CKMT1A) (pTyr153) antibodyCKMT1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
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别名
- CKMT1A
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背景
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Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
Alias Symbols: CKMT1, U-MtCK, mia-CK
Protein Interaction Partner: UBC, MDM2, SUZ12, gag-pol, CUL3, ASB9, VDAC1, SLC25A5, CKMT1A,
Protein Size: 417 -
基因ID
- 548596
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NCBI登录号
- NM_001015001, NP_001015001
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UniProt
- P12532
抗原
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