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Cathepsin F 抗体 (C-Term)

The 兔 多克隆 anti-Cathepsin F antibody is suitable to detect Cathepsin F in samples from 人. It has been validated for WB.
产品编号 ABIN5514658
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cathepsin F 抗体 (C-Term) (ABIN5514658)

抗原

See all Cathepsin F (CTSF) 抗体
Cathepsin F (CTSF)

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This Cathepsin F antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    CTSF Antibody - C-terminal region

    序列

    PLRPLCSPWL IDHAVLLVGY GNRSDVPFWA IKNSWGTDWG EKGYYYLHRG

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CTSF
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78433-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Cathepsin F (CTSF)

    别名

    CTSF

    背景

    Background Information: Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

    Gene Name: cathepsin F

    Alternative Symbols: CATSF, CLN13

    Protein Name: cathepsin F

    分子量

    53 kDa

    基因ID

    8722

    NCBI登录号

    NP_003784

    UniProt

    Q9UBX1
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