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Cathepsin F 抗体 (C-Term)

This anti-Cathepsin F antibody is a 兔 多克隆 antibody detecting Cathepsin F in WB. Suitable for 人.
产品编号 ABIN5514658
发货至: 中国

Quick Overview for Cathepsin F 抗体 (C-Term) (ABIN5514658)

抗原

See all Cathepsin F (CTSF) 抗体
Cathepsin F (CTSF)

适用

  • 34
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宿主

  • 33
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克隆类型

  • 35
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多克隆

标记

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This Cathepsin F antibody is un-conjugated

应用范围

  • 20
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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    PLRPLCSPWL IDHAVLLVGY GNRSDVPFWA IKNSWGTDWG EKGYYYLHRG

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CTSF
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Cathepsin F (CTSF)

    别名

    CTSF

    背景

    Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

    Alias Symbols: CATSF, CLN13

    Protein Size: 484

    基因ID

    8722

    NCBI登录号

    NM_003793, NP_003784

    UniProt

    Q9UBX1
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