CEP290 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for CEP290 抗体 (N-Term) (ABIN5514637)
抗原
See all CEP290 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- CEP290 Antibody - N-terminal region
-
序列
- EQLCQDIIDY QKQIDSQKET LLSRRGEDSD YRSQLSKKNY ELIQYLDEIQ
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CEP290
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80284-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- CEP290 (Centrosomal Protein 290kDa (CEP290))
-
别名
- CEP290
-
背景
-
Background Information: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
Gene Name: centrosomal protein 290 kDa
Alternative Symbols: CT87, MKS4, POC3, rd16, BBS14, JBTS5, LCA10, NPHP6, SLSN6, 3H11Ag
Protein Name: centrosomal protein of 290 kDa
-
分子量
- 88 kDa
-
基因ID
- 80184
-
NCBI登录号
- NP_079390
-
UniProt
- Q05BJ6
-
途径
- cAMP Metabolic Process, M Phase
抗原
-